Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.58 |
| ▸ | PPARG | P37231 | 16/20 | 0.58 |
| ▸ | PPARD | Q03181 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14286068 | 1.00 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL14286115 | 0.92 | PPARG (0.49) | PPARAPPARGPPARD | |
| SCHEMBL14286060 | 0.92 | PPARG (0.53) | PPARAPPARGPPARD | |
| SCHEMBL14286111 | 0.91 | PPARG (0.48) | PPARAPPARGPPARD | |
| SCHEMBL14286221 | 0.91 | PPARG (0.50) | PPARAPPARG | |
| SCHEMBL14286209 | 0.91 | PPARG (0.47) | PPARAPPARG | |
| SCHEMBL14286253 | 0.89 | PPARG (0.51) | PPARAPPARGPPARD | |
| SCHEMBL14286469 | 0.86 | PPARG (0.41) | PPARAPPARG | |
| SCHEMBL14286110 | 0.85 | PPARG (0.46) | PPARAPPARGPPARD | |
| SCHEMBL14286078 | 0.84 | MAPT (0.43) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365064-B2 | Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-04-29 | — | — | US | disclosed |
| US-7348426-B1 | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | DR. REDDY'S LABORATIES LIMITED (IN) | 2008-03-25 | — | — | US | disclosed |