SCHEMBL14286221

SCHEMBL14286221

CC(Oc1ccc(CC(Oc2ccccc2)C(=O)O)cc1)N1CCOc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.50
PPARA Q07869 18/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14286068 0.91 PPARA (0.58) PPARGPPARA
SCHEMBL14224012 0.91 PPARA (0.58) PPARGPPARA
SCHEMBL14286469 0.89 PPARG (0.41) PPARGPPARA
SCHEMBL14286060 0.89 PPARG (0.53) PPARGPPARA
SCHEMBL14286253 0.86 PPARG (0.51) PPARGPPARA
SCHEMBL14286115 0.85 PPARG (0.49) PPARGPPARA
SCHEMBL14286111 0.84 PPARG (0.48) PPARGPPARA
SCHEMBL14286209 0.84 PPARG (0.47) PPARGPPARA
SCHEMBL14286078 0.83 MAPT (0.43) PPARGPPARA
SCHEMBL14286110 0.82 PPARG (0.46) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7348426-B1 Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents DR. REDDY'S LABORATIES LIMITED (IN) 2008-03-25 US disclosed