Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224106 | 0.90 | HTR1A (0.41) | HTR1ASLC6A4PPARGPPARATSHR | |
| SCHEMBL12663596 | 0.89 | HTR1A (0.40) | HTR1ASLC6A4PPARGPPARATSHR | |
| SCHEMBL1868139 | 0.88 | PPARG (0.54) | PPARGPPARATSHRMAPTLMNA | |
| SCHEMBL4823788 | 0.88 | PPARG (0.54) | PPARGPPARATSHRMAPTLMNA | |
| SCHEMBL4827197 | 0.88 | PPARG (0.54) | PPARGPPARATSHRMAPTLMNA | |
| SCHEMBL14194946 | 0.88 | HTR1A (0.41) | HTR1ASLC6A4PPARGPPARATSHR | |
| SCHEMBL4826375 | 0.87 | PPARG (0.54) | PPARGPPARATSHRMAPTLMNA | |
| SCHEMBL14223965 | 0.86 | PPARG (0.49) | HTR1ASLC6A4PPARGPPARATSHR | |
| SCHEMBL1858905 | 0.85 | PPARG (0.45) | HTR1ASLC6A4PPARGPPARATSHR | |
| SCHEMBL4826382 | 0.85 | PPARG (0.47) | HTR1ASLC6A4PPARGPPARATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365064-B2 | Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-04-29 | — | — | US | disclosed |