Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12755613 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL12829591 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL1483298 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL1483300 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL14223988 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL14224195 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL12830089 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL14224279 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL12829639 | 0.79 | MAPT (0.47) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL1483115 | 0.77 | ALDH1A1 (0.35) | ALDH1A1MAPTLMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351841-B2 | Heterocyclic compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-04-01 | — | — | US | disclosed |