Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13156632 | 0.68 | — | — | |
| SCHEMBL645956 | 0.65 | HSD17B10 (0.41) | POLBMEN1MAPTPKMKMT2A | |
| SCHEMBL31282348 | 0.63 | POLB (0.55) | POLBMEN1MAPTPKMKMT2A | |
| SCHEMBL646657 | 0.63 | PDK2 (0.39) | POLBMEN1MAPTPKMKMT2A | |
| SCHEMBL6916799 | 0.58 | POLB (0.61) | POLBMEN1MAPTPKMKMT2A | |
| SCHEMBL29700326 | 0.58 | POLB (0.61) | POLBMEN1MAPTPKMKMT2A | |
| SCHEMBL10679407 | 0.57 | POLB (0.64) | POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL23092362 | 0.57 | POLB (0.55) | POLBALDH1A1 | |
| SCHEMBL29715299 | 0.57 | POLB (0.55) | POLBALDH1A1 | |
| SCHEMBL30681716 | 0.57 | POLB (0.46) | POLBMEN1MAPTPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045834-A2 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2008-04-17 | — | — | WO | disclosed |