Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KIFC1 | Q9BW19 | 5/20 | 0.35 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.32 |
| ▸ | MICA | Q29983 | 2/20 | 0.32 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869659 | 0.86 | ICMT (0.42) | ACEPPARAPPARGKIFC1TDP1 | |
| SCHEMBL3871897 | 0.86 | ICMT (0.42) | ACEPPARAPPARGKIFC1TDP1 | |
| SCHEMBL3871838 | 0.80 | ICMT (0.42) | ACEPPARAPPARGKIFC1TDP1 | |
| SCHEMBL4821230 | 0.80 | ICMT (0.42) | ACEPPARAPPARGKIFC1TDP1 | |
| SCHEMBL13897452 | 0.78 | CDK2 (0.38) | ACEPPARAPPARGKIFC1ITGB1 | |
| SCHEMBL3866478 | 0.72 | ICMT (0.45) | ACEPPARATDP1 | |
| SCHEMBL4816664 | 0.72 | ICMT (0.45) | ACEPPARATDP1 | |
| SCHEMBL4824666 | 0.72 | TDP1 (0.46) | ACEPPARAPPARGKIFC1SLC10A1 | |
| SCHEMBL4824661 | 0.72 | TDP1 (0.46) | ACEPPARAPPARGKIFC1SLC10A1 | |
| SCHEMBL4819544 | 0.71 | C3AR1 (0.44) | ACEPPARAPPARGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358248-B2 | Substituted amino carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | disclosed |