Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413034 | 0.82 | POLB (0.58) | KDM4ETSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4313579 | 0.80 | GAA (0.47) | KDM4ETSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL13662640 | 0.79 | KMT2A (0.64) | KDM4ETSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7358278 | 0.78 | GAA (0.57) | KDM4ETSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL13658936 | 0.77 | LMNA (0.72) | KDM4ETSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL12155334 | 0.77 | SMN1; SMN2 (0.51) | KDM4ETSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL2030080 | 0.76 | GAA (0.55) | KDM4EGAASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL8162857 | 0.74 | GAA (0.53) | KDM4ETSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4849683 | 0.74 | GAA (0.63) | KDM4EGAASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL4757619 | 0.74 | GAA (0.53) | KDM4ETSHRGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |