SCHEMBL142242

SCHEMBL142242

FC(F)(F)c1c(Cl)c[c]cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 10/20 0.43
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CHRNB2 P17787 1/20 0.32
CYP2B6 P20813 1/20 0.32
MAOA P21397 1/20 0.32
CYP2C19 P33261 1/20 0.32
CHRNA4 P43681 1/20 0.32
HTR3A P46098 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2282265 0.85 NOTUM (0.38) NOTUM
SCHEMBL2283829 0.85 NOTUM (0.38) NOTUM
SCHEMBL2282621 0.84 NOTUM (0.36) NOTUM
SCHEMBL2285498 0.84 NOTUM (0.36) NOTUM
SCHEMBL27908900 0.79 NOTUM (0.33) NOTUM
SCHEMBL27754376 0.79 NOTUM (0.34) NOTUM
SCHEMBL2285789 0.79 NOTUM (0.35) NOTUMCYP1A2CYP2C9CYP2C19
SCHEMBL2283123 0.79 NOTUM (0.33) NOTUM
SCHEMBL19356904 0.72
SCHEMBL1804500 0.72 NOTUM (0.34) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2532663-B1 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2016-03-16 EP claimed
EP-2532663-A1 Naphthalenecarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2012-12-12 EP claimed
CN-1317265-C Cyanoacrylate derivatives and their preparation method and biological activity UNIV GUIZHOU (CN) 2007-05-23 CN claimed
CN-116888124-A Bicyclic derivatives 礼蓝动物保健有限公司 2023-10-13 CN disclosed
EP-4255911-A1 BICYCLIC DERIVATIVES Elanco Tiergesundheit AG (CH) 2023-10-11 EP disclosed
US-20230303608-A1 DITHIOLENE METAL COMPLEXES BASF SCHWEIZ AG (CH) 2023-09-28 US disclosed
EP-4182395-A1 DITHIOLENE METAL COMPLEXES BASF SE (DE) 2023-05-24 EP disclosed
CN-115485342-A Dithiolene metal complexes 巴斯夫欧洲公司 2022-12-16 CN disclosed
WO-2022117783-A1 BICYCLIC DERIVATIVES ELANCO TIERGESUNDHEIT AG (CH) 2022-06-09 WO disclosed
WO-2022013081-A1 DITHIOLENE METAL COMPLEXES BASF SE (DE) 2022-01-20 WO disclosed
EP-2643416-B1 THE USE OF ARYL OR HETEROARYL SUBSTITUTED DITHIOLENE METAL COMPLEXES AS IR ABSORBERS BASF SE (DE) 2019-08-07 EP disclosed
WO-2007074137-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2007-07-05 WO disclosed
US-4698333-A Use of substituted malonic acid derivatives as agents for combating pests BAYER AKTIENGESELLSCHAFT (DE) 1987-10-06 US disclosed
EP-0118833-B1 SUBSTITUTED DIAMIDES OF PHENYLHYDROXY-THIOMALONIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1986-04-02 EP disclosed
US-4562185-A INSECTICIDES; MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1985-12-31 US disclosed
US-4556649-A Substituted malonic acid diamide insecticides, compositions and use BAYER AKTIENGESELLSCHAFT (DE) 1985-12-03 US disclosed
EP-0148499-A2 Substituted derivatives of malonic acid, process for their preparation and their use as pesticides BAYER AG (DE) 1985-07-17 EP disclosed
EP-0126235-A1 Five-membered nitrogen-containing heterocycles, process for their preparation and their use as pesticides BAYER AG (DE) 1984-11-28 EP disclosed
EP-0118833-A1 Substituted diamides of phenylhydroxy-thiomalonic acids, process for their preparation and their use as pesticides BAYER AG (DE) 1984-09-19 EP disclosed
EP-0108351-A2 Use of substituted malonic-acid derivatives as pesticides BAYER AG (DE) 1984-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303608-A1 DITHIOLENE METAL COMPLEXES TST, C1S, F12 NOTUM 2898/4885CYP1A2 1684/4885CYP2C9 2204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.