Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200595 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL6847530 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL1201087 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL1201157 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL1201058 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL1201339 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL1201447 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL4937483 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL1201490 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL1201617 | 0.85 | FDPS (0.44) | ALDH1A1L3MBTL1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351725-B2 | N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists | MERCK & CO., INC. (US) | 2008-04-01 | — | — | US | disclosed |