Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL401213 | 0.88 | ACKR3 (0.49) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL4532358 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL13654295 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL403936 | 0.80 | ACP1 (0.44) | — | |
| SCHEMBL405132 | 0.78 | CHRM4 (0.43) | ALDH1A1KDM4EKMT2AMEN1CHRM4 | |
| SCHEMBL404206 | 0.77 | MCHR1 (0.46) | KMT2ACHRM4MCHR1CYP2D6 | |
| SCHEMBL5450870 | 0.76 | HRH3 (0.41) | ALDH1A1KMT2AMEN1CHRM4HRH3 | |
| SCHEMBL403564 | 0.75 | HDAC4 (0.46) | — | |
| SCHEMBL404709 | 0.75 | MCHR1 (0.54) | KMT2AMEN1CHRM4POLBHRH3 | |
| SCHEMBL1105547 | 0.75 | SMN1; SMN2 (0.45) | ALDH1A1KMT2ACHRM4HRH3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |