Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335849 | 0.89 | KMT2A (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13219228 | 0.89 | KMT2A (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14196895 | 0.89 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL1335846 | 0.89 | KMT2A (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14525059 | 0.88 | KDM4E (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14196897 | 0.86 | KDM4E (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14196896 | 0.85 | KDM4E (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14224711 | 0.85 | KMT2A (0.44) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL17427783 | 0.83 | POLB (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14525053 | 0.81 | KDM4E (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358014-B2 | Electrophotographic organophotoreceptors with novel charge transport compounds | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-04-15 | — | — | US | disclosed |