SCHEMBL14224633

SCHEMBL14224633

CCCCCCCCCC(CCCCCCCC=O)C(CCCCCCCCC)CCCCCCCC(=O)OC1CC(C)(CC)N(OC(C)=O)C(C)(CC)C1C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 1/20 0.33
PRKCA P17252 7/20 0.32
DGKA P23743 1/20 0.32
NAAA Q02083 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1138493 0.94 NAAA (0.35) PDE4DPRKCANAAA
SCHEMBL15385303 0.94 NAAA (0.35) PDE4DPRKCANAAA
SCHEMBL13110339 0.88 NAAA (0.39) PRKCADGKANAAA
SCHEMBL1138765 0.88 NAAA (0.39) PRKCADGKANAAA
SCHEMBL10171494 0.81 NAAA (0.34) NAAA
SCHEMBL14224569 0.81 NAAA (0.40) PDE4DPRKCADGKANAAA
SCHEMBL12862569 0.75 CHRM2 (0.32)
SCHEMBL1138758 0.74 TSHR (0.34)
SCHEMBL1138498 0.73 FFAR4 (0.32)
SCHEMBL4804143 0.73 NAAA (0.43) PRKCADGKANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358365-B2 Process for the controlled increase in the molecular weight of polyethylenes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-15 US disclosed