Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111819 | 0.85 | EPHX2 (0.73) | EPHX2 | |
| SCHEMBL16111818 | 0.85 | EPHX2 (0.73) | EPHX2 | |
| SCHEMBL13805666 | 0.82 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL13295596 | 0.82 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL3294148 | 0.82 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL3294147 | 0.82 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL4653040 | 0.82 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL5845119 | 0.80 | EPHX2 (0.64) | EPHX2 | |
| SCHEMBL19542362 | 0.80 | EPHX2 (0.64) | EPHX2 | |
| SCHEMBL15643942 | 0.79 | EPHX2 (1.00) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080095711-A1 | Modulators of Pulmonary Hypertension | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080095711-A1 | Modulators of Pulmonary Hypertension | HIF1AN, PTGIS, PTGIR | EPHX2 33/4885FAAH 141/4885LPAR1 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.