⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14226939 | 1.00 | — | — | |
| SCHEMBL14151741 | 0.87 | — | — | |
| SCHEMBL14151740 | 0.87 | — | — | |
| SCHEMBL14241606 | 0.82 | — | — | |
| SCHEMBL14241607 | 0.82 | — | — | |
| SCHEMBL14151600 | 0.72 | MAP2K1 (0.36) | — | |
| SCHEMBL14151601 | 0.72 | MAP2K1 (0.36) | — | |
| SCHEMBL12540071 | 0.71 | — | — | |
| SCHEMBL14241152 | 0.68 | MAP2K1 (0.44) | — | |
| SCHEMBL14151627 | 0.68 | MAP2K1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470878-B2 | Heterocyclic sulfonamide derivatives | NOVARTIS AG (CH) | 2013-06-25 | — | — | US | disclosed |
| US-20120316149-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-12-13 | — | — | US | disclosed |