Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14230176 | 0.95 | MAPK1 (0.53) | MAPK1GAAPOLBALDH1A1MEN1 | |
| SCHEMBL14229306 | 0.94 | MEN1 (0.53) | MAPK1GAAPOLBALDH1A1MEN1 | |
| SCHEMBL14229281 | 0.92 | MAPK1 (0.55) | MAPK1GAAPOLBALDH1A1MEN1 | |
| SCHEMBL14229246 | 0.88 | MAPK1 (0.57) | MAPK1GAAPOLBALDH1A1MEN1 | |
| SCHEMBL14228994 | 0.87 | MAPK1 (0.53) | MAPK1GAAPOLBALDH1A1MEN1 | |
| SCHEMBL14229077 | 0.85 | MAPK1 (0.51) | MAPK1GAAPOLBALDH1A1MEN1 | |
| SCHEMBL14201050 | 0.84 | HPGD (0.55) | GAAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL14229423 | 0.82 | MAPK1 (0.51) | MAPK1GAAALDH1A1MEN1LMNA | |
| SCHEMBL14543581 | 0.82 | POLB (0.45) | POLBLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL20367747 | 0.82 | HDAC1 (0.67) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |