Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038794 | 0.88 | ADRB2 (0.74) | ADRB2ADRB3 | |
| SCHEMBL5038797 | 0.88 | ADRB2 (0.74) | ADRB2ADRB3 | |
| SCHEMBL14230277 | 0.87 | ADRB2 (0.78) | ADRB2ADRB3 | |
| SCHEMBL5041942 | 0.87 | ADRB2 (0.45) | ADRB2ADRB3 | |
| SCHEMBL5041951 | 0.87 | ADRB2 (0.45) | ADRB2ADRB3 | |
| SCHEMBL14452354 | 0.86 | ADRB2 (0.45) | ADRB2ADRB3 | |
| SCHEMBL14230029 | 0.86 | ADRB2 (0.78) | ADRB2ADRB3 | |
| SCHEMBL14230507 | 0.83 | ADRB2 (0.81) | ADRB2ADRB3 | |
| SCHEMBL10657723 | 0.80 | ADRB3 (0.63) | ADRB2ADRB3 | |
| SCHEMBL3917018 | 0.79 | ADRB2 (0.59) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351742-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. (US) | 2008-04-01 | — | — | US | disclosed |