Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478311 | 0.79 | CHRM3 (0.56) | HRH1KCNH2CHRM2CYP3A4ADRA2A | |
| SCHEMBL14128532 | 0.79 | CHRM3 (0.56) | HRH1KCNH2CHRM2CYP3A4ADRA2A | |
| SCHEMBL14125429 | 0.78 | KCNH2 (0.45) | HRH1KCNH2LMNACHRM2CYP3A4 | |
| SCHEMBL14029031 | 0.78 | KCNA3 (0.46) | HRH1MEN1OPRM1 | |
| SCHEMBL13557215 | 0.78 | KCNH2 (0.39) | HRH1KCNH2MEN1NPC1CACNA1F | |
| SCHEMBL2619541 | 0.78 | KCNH2 (0.45) | HRH1KCNH2LMNACHRM2CYP3A4 | |
| SCHEMBL14125383 | 0.78 | KCNA3 (0.46) | HRH1MEN1OPRM1 | |
| SCHEMBL2619538 | 0.78 | KCNA3 (0.46) | HRH1MEN1OPRM1 | |
| Hydrochloric Acid SCHEMBL14890692 | 0.77 | KCNH2 (0.44) | HRH1KCNH2LMNACHRM2CYP3A4 | |
| SCHEMBL13601296 | 0.77 | OPRM1 (0.44) | HRH1KCNH2CHRM2CYP3A4ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012166909-A1 | COMPOSITIONS AND METHODS FOR TREATING BREATHING CONTROL DISORDERS OR DISEASES | GALLEON PHARMACEUTICALS, INC. (US) | 2012-12-06 | — | — | WO | disclosed |