⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828164 | 0.82 | ALDH1A1 (0.40) | — | |
| SCHEMBL3719326 | 0.78 | — | — | |
| SCHEMBL13575346 | 0.75 | IDH1 (0.44) | — | |
| SCHEMBL4277348 | 0.73 | IDH1 (0.42) | — | |
| SCHEMBL13575341 | 0.73 | KDM4E (0.50) | — | |
| SCHEMBL21459915 | 0.70 | IDH1 (0.41) | — | |
| SCHEMBL21459913 | 0.70 | IDH1 (0.41) | — | |
| SCHEMBL4956384 | 0.67 | CYP2A6 (0.69) | — | |
| SCHEMBL31171 | 0.67 | CYP2A6 (0.69) | — | |
| SCHEMBL21459324 | 0.67 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727934-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-22 | — | — | EP | disclosed |
| EP-3773573-B1 | ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7) | MORPHIC THERAPEUTIC INC (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4704830-A2 | MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF | Septerna, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4683666-A1 | PEG TARGETING COMPOUNDS FOR DELIVERY OF THERAPEUTICS | ModernaTX, Inc. (US) | 2026-01-28 | — | — | EP | disclosed |
| US-20260014258-A1 | PEG TARGETING COMPOUNDS FOR DELIVERY OF THERAPEUTICS | MODERNATX, INC. (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250346609-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES INC (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4613332-A2 | COT MODULATORS AND METHODS OF USE THEREOF | Gilead Sciences, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2025128873-A1 | HETEROCYCLIC PYRIDINONE COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| EP-4559525-A2 | INHIBITING HUMAN INTEGRIN ALPHA4BETA7 | Morphic Therapeutic, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| EP-3896064-B1 | 4,6-DIAMINO-QUINOLINE-3-CARBONITRILE DERIVATIVES AS CANCER OSAKA THYROID (COT) MODULATORS FOR TREATING CROHN'S DISEASE AND ULCERATIVE COLITIS | GILEAD SCIENCES INC (US) | 2025-05-21 | — | — | EP | disclosed |
| US-5952360-A | Method for treating neuropathic pain | ELI LILLY AND COMPANY (US) | 1999-09-14 | — | — | US | disclosed |
| US-5942530-A | Method for treating pain | ELI LILLY AND COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0908454-A2 | Oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents | ELI LILLY AND COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0908186-A2 | Method for treating pain | ELI LILLY AND COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0908180-A2 | Use of phenyl oxazole or phenyl thiazole derivatives for treating pain | ELI LILLY AND COMPANY (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0906755-A2 | Use of phenyl oxazole or phenyl thiazole derivatives for treating neuropathic pain | ELI LILLY AND COMPANY (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1999009980-A1 | METHOD FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| EP-0373463-B1 | Process for the preparation of 2-chloro-5-chloromethyl pyridine | BAYER AG (DE) | 1995-01-18 | — | — | EP | disclosed |
| US-4958025-A | Preparation of 2-chloro-5-chloromethylpyridine | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |
| EP-0373463-A2 | Process for the preparation of 2-chloro-5-chloromethyl pyridine | BAYER AG (DE) | 1990-06-20 | — | — | EP | disclosed |