Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | NADK | O95544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441053 | 0.88 | HIF1A (0.51) | ADORA3ADORA2AHIF1APIM1CSNK2A2 | |
| SCHEMBL14253676 | 0.87 | ADORA2A (0.64) | ADORA3ADORA2AHIF1APNPLMNA | |
| SCHEMBL30366664 | 0.87 | ADORA2A (0.64) | ADORA3ADORA2AHIF1APNPLMNA | |
| SCHEMBL20419331 | 0.87 | ADORA2A (0.64) | ADORA3ADORA2AHIF1APNPLMNA | |
| SCHEMBL29283551 | 0.87 | ADORA2A (0.64) | ADORA3ADORA2AHIF1APNPLMNA | |
| SCHEMBL24420987 | 0.87 | ADORA2A (0.64) | ADORA3ADORA2AHIF1APNPLMNA | |
| SCHEMBL29673055 | 0.87 | ADORA2A (0.64) | ADORA3ADORA2AHIF1APNPLMNA | |
| SCHEMBL659995 | 0.87 | ADORA2A (0.64) | ADORA3ADORA2AHIF1APNPLMNA | |
| SCHEMBL440599 | 0.87 | ADORA2A (0.64) | ADORA3ADORA2AHIF1APNPLMNA | |
| SCHEMBL5981544 | 0.86 | HIF1A (0.52) | ADORA3ADORA2AHIF1APIM1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012164484-A1 | ADENOSINE OR DEOXYADENOSINE DERIVATIVES MODIFIED AT POSITION 8 AND A METHOD OF SYNTHESIS THEREOF | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2012-12-06 | — | — | WO | disclosed |