Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.64 |
| ▸ | NADK | O95544 | 2/20 | 0.54 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.53 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673055 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3NADKHSPA5HSPA8 | |
| SCHEMBL659995 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3NADKHSPA5HSPA8 | |
| SCHEMBL29283551 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3NADKHSPA5HSPA8 | |
| SCHEMBL14253676 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3NADKHSPA5HSPA8 | |
| SCHEMBL30366664 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3NADKHSPA5HSPA8 | |
| SCHEMBL24420987 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3NADKHSPA5HSPA8 | |
| SCHEMBL440599 | 1.00 | ADORA2A (0.64) | ADORA2AADORA3NADKHSPA5HSPA8 | |
| Phosphoric Acid SCHEMBL16208889 | 0.95 | ADORA3 (0.59) | ADORA2AADORA3NADKHSPA5HSPA8 | |
| SCHEMBL7047708 | 0.89 | ADORA3 (0.54) | ADORA2AADORA3NADKHSPA5HSPA8 | |
| SCHEMBL658005 | 0.88 | ADORA3 (0.67) | ADORA2AADORA3HSPA5HSPA8HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| WO-2018133854-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-07-26 | — | — | WO | disclosed |