Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23736085 | 0.92 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DPSMB8 | |
| SCHEMBL806691 | 0.87 | GAA (0.33) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL23736080 | 0.81 | HDAC3 (0.34) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL15750368 | 0.81 | CCNT1 (0.35) | CCNT1CDK9 | |
| SCHEMBL15727223 | 0.81 | CCNT1 (0.35) | CCNT1CDK9 | |
| SCHEMBL23736263 | 0.81 | PDE4A (0.32) | PDE4APDE4BPDE4CPDE4DPSMB8 | |
| SCHEMBL806631 | 0.81 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL15344705 | 0.80 | — | — | |
| SCHEMBL23314699 | 0.79 | PDE4A (0.30) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15344732 | 0.77 | TUBB4A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922829-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2012166665-A2 | BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2012-12-06 | — | — | WO | disclosed |