SCHEMBL14236237

SCHEMBL14236237

Nc1cc(C=O)cc(S(F)(F)(F)(F)F)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL816745 0.77 PDE2A (0.37)
SCHEMBL178489 0.77 CYP19A1 (0.46) CYP19A1
SCHEMBL9312777 0.77 PDE2A (0.37)
SCHEMBL8462178 0.77 CYP19A1 (0.40) CYP19A1
SCHEMBL22089789 0.75 ALDH1A1 (0.42)
SCHEMBL31367042 0.75 CYP2A6 (0.38)
SCHEMBL30986209 0.75 ALDH1A1 (0.42)
SCHEMBL25897376 0.71 ERN1 (0.34) CYP19A1
SCHEMBL27585754 0.71 TSHR (0.42)
SCHEMBL15123238 0.71 UNG (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115803316-A Pyridone compound and preparation method and application thereof 深圳晶泰科技有限公司 2023-03-14 CN disclosed
EP-2242740-B1 SF5 DERIVATIVES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS SANOFI SA (FR) 2012-12-12 EP disclosed