Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14128010 | 0.90 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL17685222 | 0.89 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL13865300 | 0.86 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL2332033 | 0.84 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL2502735 | 0.84 | KCNH2 (0.60) | KCNH2 | |
| Hydrochloric Acid SCHEMBL17685040 | 0.82 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL14128333 | 0.80 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL2506888 | 0.78 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL4772967 | 0.76 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL18542850 | 0.76 | SLC2A1 (0.42) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748163-B1 | PROCESS FOR PREPARING SYNTHETIC INTERMEDIATES WHICH CAN BE USED FOR MANUFACTURING ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-04-20 | — | — | EP | disclosed |
| WO-2012164498-A1 | NEW SYNTHETIC INTERMEDIATES FOR MANUFACTURING ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-12-06 | — | — | WO | disclosed |