Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 10/20 | 0.38 |
| ▸ | SCN1A | P35498 | 7/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6371270 | 0.85 | TSHR (0.41) | — | |
| Hydrochloric Acid SCHEMBL2673881 | 0.84 | TSHR (0.40) | — | |
| SCHEMBL6371366 | 0.82 | BCHE (0.49) | — | |
| Hydrochloric Acid SCHEMBL2673193 | 0.81 | BCHE (0.48) | — | |
| SCHEMBL6371941 | 0.80 | ACHE (0.48) | — | |
| Hydrochloric Acid SCHEMBL2673998 | 0.79 | ACHE (0.47) | — | |
| SCHEMBL6372506 | 0.79 | MEN1 (0.46) | SIGMAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2673933 | 0.78 | MEN1 (0.46) | SIGMAR1L3MBTL1 | |
| SCHEMBL6372810 | 0.78 | CDC7 (0.44) | LTA4H | |
| SCHEMBL6371315 | 0.77 | KDM4E (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732896-B1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMA INC (US) | 2012-12-12 | — | — | EP | disclosed |