Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1626781 | 0.99 | HTR6 (0.36) | KMT2AL3MBTL1HTR6TSHRALDH1A1 | |
| SCHEMBL14237070 | 0.87 | HTR6 (0.35) | KMT2AL3MBTL1HTR6MEN1MAPT | |
| SCHEMBL14237048 | 0.87 | HTR6 (0.39) | KMT2AL3MBTL1HTR6ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL5922603 | 0.86 | HTR6 (0.35) | KMT2AL3MBTL1HTR6TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL1627544 | 0.86 | HTR6 (0.39) | KMT2AL3MBTL1HTR6ALDH1A1MEN1 | |
| SCHEMBL14237025 | 0.85 | KMT2A (0.36) | KMT2AL3MBTL1HTR6TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL1627103 | 0.84 | KMT2A (0.36) | KMT2AL3MBTL1HTR6ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL14237064 | 0.83 | MEN1 (0.43) | KMT2AHTR6TSHRALDH1A1MEN1 | |
| SCHEMBL14237057 | 0.83 | SLC6A2 (0.34) | KMT2AL3MBTL1HTR6TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL1625086 | 0.82 | SLC6A2 (0.36) | HTR6TSHRALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831195-B1 | 5-HT7 RECEPTOR ANTAGONISTS | ESTEVE LABOR DR (ES) | 2012-12-19 | — | — | EP | claimed |