Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237119 | 0.87 | CCR2 (1.00) | CCR2 | |
| SCHEMBL14237101 | 0.84 | CCR2 (1.00) | CCR2 | |
| SCHEMBL14237138 | 0.82 | CCR2 (1.00) | CCR2 | |
| SCHEMBL14315519 | 0.81 | CCR2 (1.00) | CCR2 | |
| SCHEMBL1780947 | 0.81 | CCR2 (1.00) | CCR2 | |
| SCHEMBL14237191 | 0.79 | CCR2 (1.00) | CCR2 | |
| SCHEMBL1779544 | 0.79 | CCR2 (1.00) | CCR2 | |
| SCHEMBL1781364 | 0.79 | CCR2 (1.00) | CCR2 | |
| SCHEMBL1780101 | 0.77 | CCR2 (1.00) | CCR2 | |
| SCHEMBL14237103 | 0.77 | CCR2 (0.74) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507559-B2 | Cyclohexenyl modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-08-13 | — | — | US | claimed |
| EP-2318352-B1 | CYCLOHEXENYL COMPOUNDS AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | claimed |
| EP-2318352-B1 | CYCLOHEXENYL COMPOUNDS AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | disclosed |