Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1625092 | 0.99 | MAPT (0.42) | MAPTMEN1KMT2ATP53HTR2C | |
| SCHEMBL14237015 | 0.89 | MAPT (0.41) | MAPTMEN1KMT2ATP53HTR2C | |
| SCHEMBL14237108 | 0.88 | MEN1 (0.53) | MAPTMEN1KMT2ATP53HTR2C | |
| Hydrochloric Acid SCHEMBL1627340 | 0.88 | MAPT (0.40) | MAPTMEN1KMT2ATP53HTR2C | |
| Hydrochloric Acid SCHEMBL1625987 | 0.87 | MEN1 (0.53) | MAPTMEN1KMT2ATP53HTR2C | |
| SCHEMBL14236976 | 0.86 | KMT2A (0.36) | MAPTMEN1KMT2ATP53HTR2C | |
| Hydrochloric Acid SCHEMBL14237069 | 0.85 | KMT2A (0.35) | MAPTMEN1KMT2ATP53HTR2C | |
| SCHEMBL14236985 | 0.85 | KMT2A (0.37) | MAPTMEN1KMT2ATP53HTR2C | |
| Hydrochloric Acid SCHEMBL1627614 | 0.84 | KMT2A (0.36) | MAPTMEN1KMT2ATP53HTR2C | |
| Hydrochloric Acid SCHEMBL14237064 | 0.82 | MEN1 (0.43) | MAPTMEN1KMT2AHTR2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831195-B1 | 5-HT7 RECEPTOR ANTAGONISTS | ESTEVE LABOR DR (ES) | 2012-12-19 | — | — | EP | claimed |