Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1627340 | 0.99 | MAPT (0.40) | MAPTHTR6MEN1KMT2ATP53 | |
| SCHEMBL1629614 | 0.89 | MEN1 (0.50) | MAPTHTR6MEN1KMT2ATP53 | |
| SCHEMBL14237121 | 0.89 | MAPT (0.43) | MAPTHTR6MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL1625092 | 0.88 | MAPT (0.42) | MAPTHTR6MEN1KMT2ATP53 | |
| SCHEMBL14237000 | 0.87 | HTR6 (0.35) | MAPTHTR6KMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1626847 | 0.86 | HTR6 (0.35) | MAPTHTR6KMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL14237085 | 0.85 | HTR6 (0.35) | MAPTHTR6KMT2ALMNAALDH1A1 | |
| SCHEMBL14236989 | 0.84 | MCOLN2 (0.41) | HTR6MEN1KMT2ALMNAHPGD | |
| Hydrochloric Acid SCHEMBL1626825 | 0.83 | MCOLN2 (0.40) | MAPTHTR6MEN1KMT2ALMNA | |
| SCHEMBL14236980 | 0.83 | L3MBTL1 (0.41) | HTR6KMT2AALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831195-B1 | 5-HT7 RECEPTOR ANTAGONISTS | ESTEVE LABOR DR (ES) | 2012-12-19 | — | — | EP | claimed |