Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237284 | 0.93 | ATR (0.52) | ATR | |
| SCHEMBL14237199 | 0.90 | ATR (0.48) | ATRTYRO3 | |
| SCHEMBL3462046 | 0.85 | ATR (0.68) | ATRTYRO3 | |
| SCHEMBL3461563 | 0.84 | ATR (0.58) | ATR | |
| SCHEMBL3460317 | 0.83 | ATR (0.59) | ATRTYRO3 | |
| SCHEMBL3459975 | 0.82 | USP30 (0.55) | ATR | |
| SCHEMBL14237327 | 0.82 | ATR (0.49) | ATRTYRO3 | |
| SCHEMBL3459793 | 0.82 | ATR (0.47) | ATRTYRO3 | |
| SCHEMBL3459955 | 0.81 | ATR (0.51) | ATRTYRO3 | |
| SCHEMBL3461314 | 0.81 | ATR (0.46) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501514-B1 | PROTEIN KINASE MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2012-12-19 | — | — | EP | disclosed |