Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335722 | 0.91 | S1PR1 (0.62) | S1PR1S1PR3KCNH2S1PR5S1PR4 | |
| SCHEMBL14237345 | 0.90 | S1PR1 (0.56) | S1PR1S1PR3KCNH2S1PR5S1PR4 | |
| SCHEMBL14237186 | 0.88 | S1PR1 (0.54) | S1PR1S1PR3KCNH2S1PR5S1PR4 | |
| SCHEMBL14237139 | 0.86 | S1PR1 (0.52) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL14237308 | 0.86 | S1PR1 (0.53) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL16354000 | 0.83 | S1PR1 (0.53) | S1PR1S1PR3KCNH2S1PR5S1PR4 | |
| SCHEMBL1335888 | 0.81 | S1PR1 (0.53) | S1PR1S1PR3 | |
| SCHEMBL1335173 | 0.80 | S1PR1 (0.64) | S1PR1S1PR3KCNH2S1PR5S1PR4 | |
| SCHEMBL14237208 | 0.80 | S1PR1 (0.54) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL14237237 | 0.79 | S1PR1 (0.55) | S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382211-B1 | PYRAZOLE-I, 2, 4 -OXAD IAZOLE DERIVATIVES AS S.PHING0SINE-1-PH0SPHATE AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | claimed |