Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.39 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541394 | 0.81 | NPBWR1 (0.45) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL2547617 | 0.80 | NPBWR1 (0.52) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL2542448 | 0.79 | NPBWR1 (0.51) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL2542457 | 0.79 | NPBWR1 (0.51) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL1550872 | 0.78 | NPBWR1 (0.50) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL2546305 | 0.78 | NPBWR1 (0.49) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL1550304 | 0.78 | NPBWR1 (0.41) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL2543445 | 0.77 | NPBWR1 (0.51) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL2541771 | 0.77 | NPBWR1 (0.49) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL2544290 | 0.76 | NPBWR1 (0.48) | NPBWR1MCHR1CACNB4CACNA1ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313395-B1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | disclosed |