Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2894504 | 0.81 | KDM4E (0.54) | KDM4EMEN1KMT2ACPB2 | |
| SCHEMBL9375743 | 0.81 | KDM4E (0.51) | KDM4EMEN1KMT2ACPB2 | |
| SCHEMBL27433676 | 0.79 | KDM4E (0.48) | KDM4E | |
| SCHEMBL14167780 | 0.78 | CHRM4 (0.51) | KDM4ECHRM4 | |
| SCHEMBL9375535 | 0.78 | MAPT (0.49) | KDM4EMEN1KMT2A | |
| SCHEMBL9372804 | 0.74 | KDM4E (0.61) | KDM4EMEN1KMT2ACPB2 | |
| SCHEMBL11901224 | 0.73 | GRIN2D (0.36) | KDM4E | |
| SCHEMBL11962606 | 0.73 | CYP2E1 (0.44) | — | |
| SCHEMBL21623961 | 0.72 | KDM4E (0.51) | KDM4EMEN1KMT2A | |
| SCHEMBL11899712 | 0.72 | RAB9A (0.49) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012168315-A1 | SUBSTITUTED PIPERIDINES AS GPR119 MODULATORS FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-13 | — | — | WO | disclosed |