Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 19/20 | 0.56 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30425441 | 0.87 | NOTUM (0.60) | NPY5R | |
| SCHEMBL6026997 | 0.86 | NPY5R (0.58) | NPY5RTACR1 | |
| SCHEMBL31572868 | 0.84 | NOTUM (0.55) | NPY5R | |
| SCHEMBL13016645 | 0.82 | NPY5R (0.57) | NPY5RTACR1 | |
| SCHEMBL12153150 | 0.82 | NPY5R (0.55) | NPY5RTACR1 | |
| SCHEMBL14986299 | 0.81 | NPY5R (0.67) | NPY5RTACR1 | |
| SCHEMBL861460 | 0.80 | NPY5R (0.52) | NPY5R | |
| SCHEMBL38332 | 0.80 | NPY5R (0.55) | NPY5R | |
| SCHEMBL12568547 | 0.80 | NPY5R (0.58) | NPY5RTACR1 | |
| SCHEMBL30051797 | 0.80 | NPY5R (0.55) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282867-A1 | INDOLINE-CONTAINING SPIRO DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |
| US-20120315244-A1 | Methods for Modulation of Autophagy Through the Modulation of Autophagy-Inhibiting Gene Products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-12-13 | — | — | US | disclosed |