SCHEMBL861460

SCHEMBL861460

CS(=O)(=O)N1CC2(CC[N]CC2)c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 19/20 0.52
NOTUM Q6P988 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30425441 0.89 NOTUM (0.60) NPY5RNOTUM
SCHEMBL31572868 0.86 NOTUM (0.55) NPY5RNOTUM
SCHEMBL12568547 0.82 NPY5R (0.58) NPY5RNOTUM
SCHEMBL30051797 0.82 NPY5R (0.55) NPY5RNOTUM
SCHEMBL38332 0.82 NPY5R (0.55) NPY5RNOTUM
SCHEMBL6026997 0.82 NPY5R (0.58) NPY5R
Hydrochloric Acid SCHEMBL7123289 0.81 NPY5R (0.54) NPY5RNOTUM
Hydrochloric Acid SCHEMBL2888051 0.81 NPY5R (0.54) NPY5RNOTUM
SCHEMBL14242298 0.80 NPY5R (0.56) NPY5R
SCHEMBL30051034 0.80 NPY5R (0.52) NPY5RNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582715-A2 GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF The Administrators of the Tulane Educational Fund (US) 2013-04-24 EP claimed
WO-2011159917-A2 GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2011-12-22 WO claimed
EP-2582715-A2 GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF The Administrators of the Tulane Educational Fund (US) 2013-04-24 EP disclosed
WO-2011159917-A2 GROWTH HORMONE SECRETATOGUE RECEPTOR ANTAGONISTS AND USES THEREOF THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2011-12-22 WO disclosed