Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 16/20 | 0.34 |
| ▸ | CDK9 | P50750 | 16/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 4/20 | 0.33 |
| ▸ | CCNH | P51946 | 4/20 | 0.33 |
| ▸ | CDK4 | P11802 | 4/20 | 0.33 |
| ▸ | CCND1 | P24385 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14158109 | 0.69 | ABCB1 (0.36) | CCNT1CDK9DPP4CDK7CCNH | |
| SCHEMBL14242902 | 0.68 | PDE10A (0.61) | DPP4PDE10A | |
| SCHEMBL21212195 | 0.62 | PDE10A (0.51) | CCNT1CDK9CDK7CCNHCDK4 | |
| SCHEMBL14158421 | 0.60 | DYRK1A (0.40) | DPP4PDE10ACDK5CDK5R1 | |
| SCHEMBL14242905 | 0.59 | CSNK2B (0.42) | — | |
| SCHEMBL20664459 | 0.59 | PDE10A (0.43) | CCNT1CDK9CCNE1CDK2MAPK8 | |
| SCHEMBL3460690 | 0.58 | PIK3CG (0.48) | PDE10A | |
| SCHEMBL1073271 | 0.57 | MAP3K5 (0.49) | CDK2 | |
| SCHEMBL14158143 | 0.57 | KMT2A (0.38) | DPP4CCNE1CDK2HTR1DHTR3A | |
| SCHEMBL25807858 | 0.57 | CCNT1 (0.54) | CCNT1CDK9CDK7CCNHCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |