Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073900 | 0.80 | PDE10A (0.43) | PIK3CGALDH1A1PDE10A | |
| SCHEMBL9300367 | 0.80 | PDE10A (0.43) | PIK3CGALDH1A1PDE10A | |
| SCHEMBL29344715 | 0.80 | PDE10A (0.67) | NPC1RAB9APDE10A | |
| SCHEMBL20664459 | 0.80 | PDE10A (0.43) | KDM4ENPC1RAB9APDE10A | |
| SCHEMBL4431791 | 0.80 | ALDH1A1 (0.50) | PIK3CGKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL4102510 | 0.80 | PDE10A (0.43) | PIK3CGKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL10408224 | 0.80 | PDE10A (0.43) | PIK3CGKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9301157 | 0.80 | PDE10A (0.43) | PIK3CGKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL20406305 | 0.80 | PDE10A (0.43) | PIK3CGKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL659433 | 0.80 | PDE10A (0.67) | PIK3CGKDM4ENPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109712-A1 | RIFAMYCINS FOR NONTUBERCULOUS MYCOBACTERIA | UNIV MINNESOTA (US) | 2026-04-23 | — | — | US | disclosed |
| EP-4598930-A1 | RIFAMYCINS FOR NONTUBERCULOUS MYCOBACTERIA | Regents of the University of Minnesota (US) | 2025-08-13 | — | — | EP | disclosed |
| EP-4107159-B1 | 5-(3-(ETHYLSULFONYL)PYRIDIN-2-YL)-PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDE AND INSECTICIDE AGENTS FOR CROP PROTECTION | PI INDUSTRIES LTD (IN) | 2024-04-17 | — | — | EP | disclosed |
| WO-2024076693-A1 | RIFAMYCINS FOR NONTUBERCULOUS MYCOBACTERIA | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-04-11 | — | — | WO | disclosed |
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2022-12-13 | — | — | US | disclosed |
| US-20210323975-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO EARLY DISCOVERY, INC. | 2021-10-21 | — | — | US | disclosed |
| CN-107208279-B | Etching solution, replenishment solution, and method for forming copper wiring | MEC股份有限公司 | 2021-03-26 | — | — | CN | disclosed |
| US-20200239439-A1 | HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2020-07-30 | — | — | US | disclosed |
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |
| WO-2019148005-A1 | INHIBITORS OF CBL-B AND METHODS OF USE THEREOF | NURIX THERAPEUTICS, INC. (US) | 2019-08-01 | — | — | WO | disclosed |
| US-5635495-A | ANTIARTHRITIC AGENTS TREATING BONE DISORDER, OSTEOPOROSIS; CALCIUM CHANNEL BLOCKERS | THE UPJOHN COMPANY (US) | 1997-06-03 | — | — | US | disclosed |
| EP-0593575-B1 | PYRAZOLOPYRIMIDINE AND PYRIMIDINYL BISPHOSPHONIC ESTERS AS ANTI-INFLAMMATORIES | UPJOHN CO (US) | 1997-05-07 | — | — | EP | disclosed |
| CN-1119941-A | Use of purimifdinyl bisphophonic esters for the preparation of a medicament for treating of inflammatin | UPJOHN CO (US) | 1996-04-10 | — | — | CN | disclosed |
| EP-0663919-A1 | PYRIMIDINE BISPHOSPHONATE ESTERS AS ANTI-INFLAMATORIES | PHARMACIA & UPJOHN COMPANY (US) | 1995-07-26 | — | — | EP | disclosed |
| US-5397774-A | Pyrazolopyrimidine and pyrimidinyl bisphosphonic esters as anti-inflammatories | THE UPJOHN COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| WO-1994009017-A1 | PYRIMIDINE BISPHOSPHONATE ESTERS AND (ALKOXYMETHYLPHOSPHINYL)ALKYL PHOSPHONIC ACIDS AS ANTI-INFLAMMATORIES | THE UPJOHN COMPANY (US) | 1994-04-28 | — | — | WO | disclosed |
| EP-0593575-A1 | PYRAZOLOPYRIMIDINE AND PYRIMIDINYL BISPHOSPHONIC ESTERS AS ANTI-INFLAMMATORIES. | UPJOHN CO (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993001198-A1 | PYRAZOLOPYRIMIDINE AND PYRIMIDINYL BISPHOSPHONIC ESTERS AS ANTI-INFLAMMATORIES | THE UPJOHN COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| EP-0521622-A1 | Pyrazolopyrimidine and pyrimidinyl bisphosphonic esters as anti-inflammatories | THE UPJOHN COMPANY (US) | 1993-01-07 | — | — | EP | disclosed |
| US-4093617-A | ENZYME INHIBITORS | ICN PHARMACEUTICALS, INC. (US) | 1978-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | USP28, USP25, USP24 | PIK3CG 2487/4885KDM4E 403/4885NPC1 3743/4885 |
| US-20260109712-A1 | RIFAMYCINS FOR NONTUBERCULOUS MYCOBACTERIA | RIF1, MRPL21, NRDC | PIK3CG 3730/4885KDM4E 4476/4885NPC1 94/4885 |
| US-20210323975-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | USP28, USP25, USP24 | PIK3CG 2487/4885KDM4E 403/4885NPC1 3743/4885 |
| US-20200239439-A1 | HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME | CXCR4, CXCL12, CXCR1 | PIK3CG 463/4885KDM4E 4466/4885NPC1 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.