Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846612 | 0.84 | GPR35 (0.53) | DEGS1PTGS1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL1026009 | 0.81 | KDR (0.55) | DEGS1PTGS1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL15850231 | 0.70 | MAPT (0.49) | DEGS1KMT2AMEN1NPC1LMNA | |
| SCHEMBL31013252 | 0.69 | KDR (0.54) | KCNQ3KCNQ2KCNE1KCNQ1KMT2A | |
| SCHEMBL20284467 | 0.69 | DEGS1 (1.00) | DEGS1PTGS1TRPV1 | |
| SCHEMBL5645475 | 0.69 | KCNQ3 (0.72) | DEGS1PTGS1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL19474952 | 0.68 | CYP1A2 (0.50) | KMT2AMEN1MAPTKDM4ERXFP1 | |
| SCHEMBL19475066 | 0.68 | PTPN5 (0.48) | KMT2AMEN1LMNAKDM4E | |
| SCHEMBL1027433 | 0.68 | KDR (0.58) | PTGS1KMT2AMEN1NPC1LMNA | |
| SCHEMBL14243236 | 0.68 | GPR35 (0.59) | PTGS1KMT2AMEN1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170867-A1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2012-12-13 | — | — | WO | disclosed |