Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243147 | 0.87 | CSNK2B (0.31) | — | |
| SCHEMBL14243322 | 0.75 | CSNK2B (0.31) | — | |
| SCHEMBL12841000 | 0.72 | CSNK2B (0.31) | — | |
| SCHEMBL14158437 | 0.72 | CSNK2B (0.42) | PIM1PIM3PIM2ESRRA | |
| SCHEMBL14158442 | 0.72 | CSNK2B (0.42) | PIM1PIM3PIM2ESRRA | |
| SCHEMBL14243320 | 0.72 | CSNK2B (0.32) | — | |
| SCHEMBL1486086 | 0.71 | CSNK2B (0.41) | GPR119 | |
| SCHEMBL1486088 | 0.71 | CSNK2B (0.41) | GPR119 | |
| SCHEMBL14242630 | 0.70 | PIM1 (0.37) | PIM1PIM3PIM2ESRRA | |
| SCHEMBL2051260 | 0.69 | CSNK2B (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |