SCHEMBL14243147

SCHEMBL14243147

CC(C)(C)OC(=O)N(c1cc(C2CC=C(C#N)S2)nc2c(C=O)cnn12)C1CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CSNK2B P67870 1/20 0.31
RET P07949 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14243322 0.87 CSNK2B (0.31) CSNK2B
SCHEMBL14243447 0.87 PIM1 (0.34)
SCHEMBL14243320 0.84 CSNK2B (0.32) CSNK2B
SCHEMBL12841000 0.82 CSNK2B (0.31) CSNK2B
SCHEMBL1527843 0.81 GPR119 (0.41) CSNK2BRET
SCHEMBL2028635 0.79 GPR119 (0.37) CSNK2B
SCHEMBL14242903 0.79 CSNK2B (0.32) CSNK2B
SCHEMBL2026049 0.79 CSNK2B (0.38) CSNK2B
SCHEMBL12645224 0.79 CSNK2B (0.32) CSNK2B
SCHEMBL2030073 0.78 CSNK2B (0.31) CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012170827-A2 PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS CYLENE PHARMACEUTICALS, INC. (US) 2012-12-13 WO disclosed