Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999555 | 0.89 | GAA (0.38) | GAARAD52KMT2AKEAP1SMN1; SMN2 | |
| SCHEMBL26115598 | 0.84 | GAA (0.38) | GAARAD52KMT2A | |
| SCHEMBL1829660 | 0.83 | THRB (0.39) | GAARAD52KMT2AKEAP1SMN1; SMN2 | |
| SCHEMBL16292376 | 0.83 | GAA (0.37) | GAARAD52KMT2AKEAP1SMN1; SMN2 | |
| SCHEMBL16143361 | 0.82 | GAA (0.51) | GAARAD52KMT2AKEAP1SMN1; SMN2 | |
| SCHEMBL24230216 | 0.82 | GAA (0.34) | GAARAD52KMT2AKEAP1SMN1; SMN2 | |
| SCHEMBL8265735 | 0.81 | KMT2A (0.37) | GAARAD52KMT2A | |
| SCHEMBL26177116 | 0.81 | KMT2A (0.37) | GAARAD52KMT2A | |
| SCHEMBL25165704 | 0.81 | KMT2A (0.37) | GAARAD52KMT2A | |
| SCHEMBL1700249 | 0.81 | THRB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |