Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247646 | 0.88 | BRD4 (0.42) | CNR2BRD4 | |
| SCHEMBL3779780 | 0.85 | BACE1 (0.52) | CNR2 | |
| SCHEMBL4000754 | 0.81 | CNR2 (0.68) | CNR2CNR1 | |
| SCHEMBL14466814 | 0.80 | PIK3CA (0.43) | CNR2CNR1BRD4 | |
| SCHEMBL3999287 | 0.80 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL20641274 | 0.80 | AURKA (0.47) | BRD4 | |
| SCHEMBL18650914 | 0.76 | BRD4 (0.46) | CNR2CNR1BRD4 | |
| SCHEMBL14317279 | 0.72 | BRD4 (0.42) | CNR2BRD4 | |
| SCHEMBL12290596 | 0.72 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL1609531 | 0.72 | CNR2 (0.68) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |