Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247641 | 0.88 | CNR2 (0.47) | BRD4CNR2 | |
| SCHEMBL14317279 | 0.85 | BRD4 (0.42) | BRD4BAZ2ACNR2BACE1TLR8 | |
| SCHEMBL4000754 | 0.75 | CNR2 (0.68) | CNR2 | |
| SCHEMBL21307563 | 0.74 | POLB (0.62) | KMT2ABACE1TLR8NUDT1ALOX15 | |
| SCHEMBL3999287 | 0.73 | CNR2 (0.57) | CNR2 | |
| SCHEMBL3779780 | 0.72 | BACE1 (0.52) | CNR2BACE1NUDT1 | |
| SCHEMBL14466814 | 0.71 | PIK3CA (0.43) | BRD4CNR2TLR8 | |
| SCHEMBL14247511 | 0.71 | ALOX15 (0.53) | KMT2ATLR8ALOX15MAPK1CXCR4 | |
| SCHEMBL14447547 | 0.69 | TLR8 (0.51) | KMT2ABACE1TLR8NUDT1CXCR4 | |
| SCHEMBL21311091 | 0.69 | CNR2 (0.39) | BRD4BAZ2ACNR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |