Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14248140 | 1.00 | MEN1 (0.49) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL14248570 | 0.92 | MEN1 (0.51) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL14248432 | 0.91 | MEN1 (0.48) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL261310 | 0.89 | MEN1 (0.44) | MEN1GAAKMT2AKDM4EFOXO1 | |
| SCHEMBL261692 | 0.89 | MEN1 (0.48) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL14248150 | 0.89 | MEN1 (0.48) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL262926 | 0.87 | MEN1 (0.49) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL14248445 | 0.86 | MEN1 (0.46) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL14248448 | 0.86 | MEN1 (0.46) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL14247997 | 0.85 | MEN1 (0.49) | MEN1GAAKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174013-A2 | TREATMENT OF CARDIOVASCULAR DISEASE, STROKE, AND INFLAMMATORY CONDITIONS | CARDEUS PHARMACEUTICALS, INC. (US) | 2012-12-20 | — | — | WO | disclosed |