SCHEMBL14248574

SCHEMBL14248574

CC1(Cc2ccc3c(c2)OCO3)CO1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.51
TAAR1 Q96RJ0 4/20 0.50
SLC6A4 P31645 3/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A3 Q01959 2/20 0.50
MIF P14174 1/20 0.49
CYP1A2 P05177 2/20 0.49
MAPT P10636 1/20 0.49
CYP2D6 P10635 3/20 0.47
CYP2C19 P33261 2/20 0.47
HTT P42858 1/20 0.47
CMA1 P23946 1/20 0.46
ALDH1A1 P00352 2/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29667022 0.81 CYP3A4 (0.50) CYP3A4TAAR1SLC6A4SLC6A2SLC6A3
SCHEMBL28124497 0.74 CYP3A4 (0.55) CYP3A4TAAR1CYP1A2CYP2D6CYP2C19
SCHEMBL92784 0.74 TAAR1 (0.60) CYP3A4TAAR1SLC6A4SLC6A2SLC6A3
SCHEMBL108087 0.73 TAAR1 (0.77) CYP3A4TAAR1SLC6A4SLC6A2SLC6A3
SCHEMBL109195 0.73 TAAR1 (0.64) CYP3A4TAAR1SLC6A4SLC6A2SLC6A3
SCHEMBL6630039 0.73 CYP3A4 (0.62) CYP3A4TAAR1SLC6A4SLC6A2SLC6A3
SCHEMBL108109 0.71 TAAR1 (0.62) CYP3A4TAAR1SLC6A4SLC6A2SLC6A3
SCHEMBL529821 0.71 TAAR1 (0.62) CYP3A4TAAR1SLC6A4SLC6A2SLC6A3
Ethane SCHEMBL11863120 0.71 CYP3A4 (0.61) CYP3A4TAAR1SLC6A4SLC6A2SLC6A3
SCHEMBL429483 0.71 TAAR1 (0.67) CYP3A4TAAR1SLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012173842-A2 PURIFICATION PROCESS FOR PARA-METHALLYLPYROCATECHOL FMC CORPORATION (US) 2012-12-20 WO claimed
WO-2012173842-A2 PURIFICATION PROCESS FOR PARA-METHALLYLPYROCATECHOL FMC CORPORATION (US) 2012-12-20 WO disclosed
WO-2012173842-A2 PURIFICATION PROCESS FOR PARA-METHALLYLPYROCATECHOL FMC CORPORATION (US) 2012-12-20 WO disclosed