Valine

Valine

SCHEMBL1424875

CC(C)[C@H](N)C(=O)O.Oc1ccc(O)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.68
LMNA P02545 2/20 0.44
NR1I2 O75469 1/20 0.44
PTGS1 P23219 1/20 0.44
ADRA1A P35348 1/20 0.44
BLM P54132 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TAAR1 Q96RJ0 3/20 0.43
SLC6A2 P23975 1/20 0.43
SLC1A3 P43003 3/20 0.43
SLC1A2 P43004 3/20 0.43
SLC1A1 P43005 3/20 0.43
MEN1 O00255 2/20 0.43
CYP1A2 P05177 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL5324319 0.92 SLC7A5 (0.58) SLC7A5LMNANR1I2PTGS1ADRA1A
Valine SCHEMBL754999 0.91 SLC7A5 (0.62) SLC7A5LMNANR1I2PTGS1ADRA1A
Valine SCHEMBL5479272 0.91 SLC7A5 (0.62) SLC7A5LMNANR1I2PTGS1ADRA1A
P-Nitrophenol SCHEMBL4805916 0.84 SLC1A3 (0.50) SLC7A5TDP1SLC1A3SLC1A2SLC1A1
Valine SCHEMBL2587287 0.84 SLC7A5 (0.71) SLC7A5LMNANR1I2PTGS1ADRA1A
Hydroquinone SCHEMBL15655103 0.83 SLC7A5 (0.54) SLC7A5LMNABLMTAAR1SLC6A2
Valine SCHEMBL28052598 0.83 SLC7A5 (0.88) SLC7A5LMNANR1I2PTGS1ADRA1A
Valine SCHEMBL4582565 0.83 SLC7A5 (0.88) SLC7A5LMNANR1I2PTGS1ADRA1A
Valine SCHEMBL43678 0.83
Valine SCHEMBL8515 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9334504-B2 High throughput transfection of filamentous fungi DSM IP ASSETS B.V. (NL) 2016-05-10 US disclosed
US-20140178932-A1 HIGH THROUGHPUT TRANSFECTION OF FILAMENTOUS FUNGI DSM IP ASSETS B.V. (NL) 2014-06-26 US disclosed
US-8697364-B2 High throughput transfection of filamentous fungi DSM IP ASSETS B.V. (NL) 2014-04-15 US disclosed
EP-2032703-B1 HIGH THROUGHPUT TRANSFECTION OF FILAMENTOUS FUNGI DSM IP ASSETS BV (NL) 2011-03-23 EP disclosed
US-20090280529-A1 HIGH THROUGHPUT TRANSFECTION OF FILAMENTOUS FUNGI DSM IP ASSETS B.V. (NL) 2009-11-12 US disclosed
US-4835323-A Hydroquinones CIBA-GEIGY AG (CH) 1989-05-30 US disclosed
US-4484000-A PHOTOGRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1984-11-20 US disclosed