Valine

Valine

SCHEMBL5324319

CC(C)[C@H](N)C(=O)O.Nc1ccc(O)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.58
HIF1A Q16665 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CA3 P07451 1/20 0.50
CYP3A4 P08684 1/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50
CA6 P23280 1/20 0.50
CASP1 P29466 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CA14 Q9ULX7 1/20 0.50
SLC1A3 P43003 3/20 0.42
SLC1A2 P43004 3/20 0.42
SLC1A1 P43005 3/20 0.42
APP P05067 2/20 0.41
ESR1 P03372 1/20 0.40
CYP19A1 P11511 1/20 0.40
ESR2 Q92731 1/20 0.40
LMNA P02545 2/20 0.40
MMP1 P03956 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL1424875 0.92 SLC7A5 (0.68) SLC7A5HIF1ACA3CYP3A4CA6
4-Aminophenol SCHEMBL6661712 0.86 THRB (0.56) SLC7A5HIF1AALDH1A1CA3CYP3A4
Valine SCHEMBL5479272 0.84 SLC7A5 (0.62) SLC7A5HIF1ACA3CA14SLC1A3
Valine SCHEMBL6639200 0.84 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1PTGS1
Valine SCHEMBL754999 0.84 SLC7A5 (0.62) SLC7A5HIF1ACA3CA14SLC1A3
Tyramine SCHEMBL9719619 0.81 TAAR1 (0.58) SLC7A5ALDH1A1SLC1A3SLC1A2SLC1A1
Dapsone SCHEMBL7800695 0.80 HTR6 (0.55) SLC7A5ALDH1A1CYP3A4SLC1A3SLC1A2
Valine SCHEMBL10506548 0.79 SLC7A5 (0.56) SLC7A5ALDH1A1CYP3A4THRBSLC1A3
Arsanilic Acid SCHEMBL5053918 0.79 TSHR (0.60) SLC7A5ALDH1A1ALOX15CA6HSD17B10
Sulfanilamide SCHEMBL812096 0.79 CA2 (0.57) SLC7A5CA3CA6CA14SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007147829-A1 AZOLOPYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING HARMFUL FUNGI BASF SE (DE) 2007-12-27 WO disclosed