Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3016722 | 0.85 | YTHDC1 (0.57) | YTHDC1CYP2C19CYP1A2TSHRFLT3 | |
| SCHEMBL14249375 | 0.85 | YTHDC1 (0.57) | YTHDC1CYP2C19CYP1A2TSHRFLT3 | |
| SCHEMBL3029027 | 0.82 | YTHDC1 (0.60) | YTHDC1CYP2C19CYP1A2TSHRFLT3 | |
| SCHEMBL14248883 | 0.82 | YTHDC1 (0.60) | YTHDC1CYP2C19CYP1A2TSHRFLT3 | |
| SCHEMBL3025868 | 0.82 | YTHDC1 (0.60) | YTHDC1CYP2C19CYP1A2TSHRFLT3 | |
| SCHEMBL13765749 | 0.81 | YTHDC1 (0.62) | YTHDC1CYP2C19CYP1A2TSHRFLT3 | |
| SCHEMBL14296940 | 0.81 | YTHDC1 (0.60) | YTHDC1CYP2C19CYP1A2TSHRFLT3 | |
| SCHEMBL14250027 | 0.81 | YTHDC1 (0.60) | YTHDC1CYP2C19CYP1A2TSHRFLT3 | |
| SCHEMBL14248878 | 0.81 | YTHDC1 (0.52) | YTHDC1CYP2C19CYP1A2TSHRFLT3 | |
| SCHEMBL14296947 | 0.80 | YTHDC1 (0.54) | YTHDC1CYP2C19CYP1A2TSHRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012172043-A1 | PURINE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS FOR PREVENTION OR TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRE BIODIM (FR) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012172043-A1 | PURINE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS FOR PREVENTION OR TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRE BIODIM (FR) | 2012-12-20 | — | — | WO | disclosed |