YTHDC1

YTH domain-containing protein 1 · Q96MU7 · YTHDC1 on Sugi Atlas →

8,776 patent compounds predicted against YTHDC1, 4,565 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2060052 SCHEMBL2060052 0.57 13/20
SCHEMBL130696 SCHEMBL130696 0.47 12/20
SCHEMBL1322651 SCHEMBL1322651 0.78 11/20
SCHEMBL3133851 SCHEMBL3133851 0.36 11/20
SCHEMBL183249 SCHEMBL183249 0.70 10/20
SCHEMBL1321679 SCHEMBL1321679 0.73 9/20
SCHEMBL183057 SCHEMBL183057 0.68 9/20
SCHEMBL1655538 SCHEMBL1655538 0.64 9/20
SCHEMBL3131580 SCHEMBL3131580 0.35 9/20
SCHEMBL1321678 SCHEMBL1321678 0.72 8/20
SCHEMBL786075 SCHEMBL786075 0.62 8/20
SCHEMBL822916 SCHEMBL822916 0.57 8/20
SCHEMBL690985 SCHEMBL690985 0.53 8/20
SCHEMBL1578361 SCHEMBL1578361 0.46 8/20
SCHEMBL3130220 SCHEMBL3130220 0.40 8/20
SCHEMBL3133540 SCHEMBL3133540 0.40 8/20
SCHEMBL3133504 SCHEMBL3133504 0.72 7/20
SCHEMBL185397 SCHEMBL185397 0.62 7/20
SCHEMBL3137129 SCHEMBL3137129 0.58 7/20
SCHEMBL3137298 SCHEMBL3137298 0.48 7/20

Clinical trials — most relevant to YTHDC1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment PHASE2COMPLETED
Neoadjuvant Aitua (PD-1/CTLA-4 Bispecific) Plus Nab-Paclitaxel and Carboplatin for Advanced High-Grade Serous Ovarian Cancer PHASE2NOT_YET_RECRUITING
A Study of HDM2005 in Patients With Advanced Solid Tumor PHASE1RECRUITING
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Prognosis of METTL-14 in Endometrial Carcinoma nanNOT_YET_RECRUITING
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study nanNOT_YET_RECRUITING
Using the Epitranscriptome to Diagnose and Treat Gliomas nanRECRUITING
The Molecular Pathogenesis Study of Cataract nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
MEHMO Natural History and Biomarkers nanRECRUITING
Long Term Prediction of MASH-related HCC Risk by Proteomics nanNOT_YET_RECRUITING
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs nanUNKNOWN
Neurofeedback in Clinical High Risk nanNOT_YET_RECRUITING
Genetic Risk Factors for Multi-system Inflammatory Syndrome in Children and Pediatric Post COVID Condition nanUNKNOWN
Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants nanRECRUITING
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal Cancer nanNOT_YET_RECRUITING
The Role of FTO Gene Polymorphism and Insulin Preparation in Obesity in Children With Type 1 Diabetes Mellitus nanCOMPLETED
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cancer Patients nanCOMPLETED
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Evaluation of Brain Dysfunction in Patients with Duchene Muscular Dystrophy nanNOT_YET_RECRUITING
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Predictors of Post-COVID-19 Clinical and Cognitive Consequences nanRECRUITING
Effect of DNMT SNPs on DNA Methylation in Primary ITP nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a YTHDC1 binder may also engage these)

ProteinNameSimilarity
E9Q5K9 1.000 E9Q5K9 →
Q9QY02 1.000 Q9QY02 →
P97868 0.994 P97868 →
Q14AX6 0.992 Q14AX6 →
Q3MJK5 0.991 Q3MJK5 →
P30415 0.990 P30415 →
Q5HZJ0 0.990 Q5HZJ0 →
Q9D824 0.990 Q9D824 →
PPHLN1 Periphilin-1 0.989 landscape →
Q62504 0.989 Q62504 →
Q9V468 0.989 Q9V468 →
Q1LUE5 0.988 Q1LUE5 →
Q6H7U2 0.988 Q6H7U2 →
Q5VTL8 0.988 Q5VTL8 →
Q66J90 0.988 Q66J90 →
Q9CSP9 0.988 Q9CSP9 →
Q9NRR4 0.988 Q9NRR4 →
F1Q8W0 0.988 F1Q8W0 →
Q15424 0.988 Q15424 →
Q9LY75 0.988 Q9LY75 →
Q14151 0.988 Q14151 →
FIP1L1 Pre-mRNA 3'-end-processing factor FIP1 0.988 landscape →
SLTM SAFB-like transcription modulator 0.987 landscape →
E1BB50 0.987 E1BB50 →
Q6E3D4 0.987 Q6E3D4 →
E9Q784 0.987 E9Q784 →
Q8TAD8 0.987 Q8TAD8 →
A0A0R4IZ84 0.987 A0A0R4IZ84 →
Q5RAA7 0.987 Q5RAA7 →
D3YXK2 0.987 D3YXK2 →