SCHEMBL1424934

SCHEMBL1424934

OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@H](n3cc(-c4ccccc4C(F)(F)F)nn3)[C@H]2O)[C@H](O)[C@@H](n2cc(-c3ccccc3C(F)(F)F)nn2)[C@H]1O

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 20/20 0.69
LGALS1 P09382 12/20 0.69
LGALS8 O00214 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1955667 1.00 LGALS3 (0.69) LGALS3LGALS1LGALS8
SCHEMBL15806280 0.87 LGALS3 (0.55) LGALS3LGALS1LGALS8
SCHEMBL12572816 0.87 LGALS3 (0.55) LGALS3LGALS1LGALS8
SCHEMBL1955106 0.87 LGALS3 (0.83) LGALS3LGALS1LGALS8
SCHEMBL1955104 0.87 LGALS3 (0.83) LGALS3LGALS1LGALS8
SCHEMBL17935486 0.79 LGALS3 (0.74) LGALS3LGALS1LGALS8
SCHEMBL19630740 0.79 LGALS3 (0.74) LGALS3LGALS1LGALS8
SCHEMBL19630739 0.79 LGALS3 (0.74) LGALS3LGALS1LGALS8
SCHEMBL19630716 0.79 LGALS3 (0.74) LGALS3LGALS1LGALS8
SCHEMBL3284264 0.79 LGALS3 (0.80) LGALS3LGALS1LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2297174-B1 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS GALECTO BIOTECH AB (DK) 2015-07-08 EP disclosed
US-20140171630-A1 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS GALECTO BIOTECH AB (SE) 2014-06-19 US disclosed
US-8697862-B2 Synthesis of galactoside inhibitors GALECTO BIOTECH AB (SE) 2014-04-15 US disclosed
US-20140011765-A1 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS GALECTO BIOTECH AB (SE) 2014-01-09 US disclosed
US-20110130553-A1 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS GALECTO BIOTECH AB (SE) 2011-06-02 US disclosed
EP-2297174-A1 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS Forskarpatent i Syd AB (SE) 2011-03-23 EP disclosed
WO-2009139719-A9 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS FORSKARPATENT I SYD AB (SE) 2010-05-06 WO disclosed
WO-2009139719-A1 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS FORSKARPATENT I SYD AB (SE) 2009-11-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140011765-A1 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS ST6GAL1, GALNT10, ST3GAL3 LGALS3 40/4885LGALS1 50/4885LGALS8 49/4885
US-20110130553-A1 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS ST6GAL1, GALNT10, ST3GAL3 LGALS3 40/4885LGALS1 50/4885LGALS8 49/4885
US-20140171630-A1 NOVEL SYNTHESIS OF GALACTOSIDE INHIBITORS ST6GAL1, GALNT10, ST3GAL3 LGALS3 40/4885LGALS1 50/4885LGALS8 49/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.