SCHEMBL1425019

SCHEMBL1425019

O=C(Nc1nc2nc[nH]c2c(=O)[nH]1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.65
BRD4 O60885 1/20 0.55
ADORA2A P29274 2/20 0.50
NPC1 O15118 1/20 0.50
PKM P14618 1/20 0.50
MAOB P27338 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
STAT3 P40763 1/20 0.49
ADORA3 P0DMS8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28251689 0.87 GDA (0.62) GDANPC1RAB9A
SCHEMBL28004978 0.87 GDA (0.62) GDA
SCHEMBL28004452 0.86 GDA (0.57) GDANPC1RAB9A
SCHEMBL29411658 0.83 GDA (0.76) GDA
SCHEMBL28004595 0.83 GDA (0.60) GDA
SCHEMBL6222949 0.81 GDA (0.61) GDA
SCHEMBL5198603 0.81 GDA (0.61) GDA
Hypoxanthine SCHEMBL27727730 0.81 GDA (0.72) GDA
SCHEMBL1425017 0.80 ADORA2A (0.52) BRD4ADORA2ANPC1PKMMAOB
SCHEMBL28251697 0.80 ADORA2A (0.51) BRD4ADORA2ANPC1PKMMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
CN-106117289-B 2 '-O-MOE-3 '-H- thiophosphate nucleoside monomers and its synthetic method 郑州大学 2019-02-12 CN claimed
WO-1992011276-A1 NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1992-07-09 WO claimed
JP-58198500-A None JP disclosed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO disclosed
US-20250011359-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2025-01-09 US disclosed
CN-113564168-B Methods of preparing polynucleotides using multivalent cation salt compositions 美国杰龙生物医药公司 2024-10-25 CN disclosed
US-20240150391-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME GERON CORP (US) 2024-05-09 US disclosed
CN-117412753-A Bruton's tyrosine kinase inhibitors and methods of use thereof 詹森药业有限公司 2024-01-16 CN disclosed
CN-117357548-A Oligonucleotide composition and method for preparing same 美国杰龙生物医药公司 2024-01-09 CN disclosed
EP-4286519-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME GERON CORPORATION (US) 2023-12-06 EP disclosed
CN-1127749-A Amino acid-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent and a medicament containing them HOECHST AG (DE) 1996-07-31 CN disclosed
EP-0700899-A1 Substituted benzoylguanidines, a process for their preparation, their use as drug or diagnostic agents as well as medicaments containing them HOECHST AKTIENGESELLSCHAFT (DE) 1996-03-13 EP disclosed
US-5216141-A OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR LINKAGES BENNER, STEVEN 1993-06-01 US disclosed
EP-0418309-A4 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR 1993-01-07 EP disclosed
WO-1992011276-A1 NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1992-07-09 WO disclosed
EP-0418309-A1 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR BENNER, Steven Albert (CH) 1991-03-27 EP disclosed
WO-1989012060-A1 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR BENNER STEVEN ALBERT (CH) 1989-12-14 WO disclosed
EP-0105486-A2 1-Monophosphate esters, 1,3-bisphosphate esters and cyclic phosphate esters of 9-(1,3-dihydroxy-2-propoxymethyl)-guanine as antiviral agents SYNTEX (U.S.A.) INC. (US) 1984-04-18 EP disclosed
JP-S58198500-A RIBONUCLEOSIDE SUBSTITUTED WITH 4-METHOXYBENZYL GROUP IN THE 2'-POSITION MITSUI TOATSU CHEM INC 1983-11-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150391-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME RNGTT, NSUN2, POLN GDA 725/4885BRD4 4599/4885ADORA2A 829/4885
US-20250011359-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME RNGTT, NSUN2, POLN GDA 725/4885BRD4 4599/4885ADORA2A 829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.